Our laboratory uses human tissue culture and yeast to further define the mechanisms underlying human diseases of making ribosomes. Recent work has been on ANE syndrome (eLife 2016), North American Childhood Cirrhosis (PLoS Genetics 2012) and a new ribosomopathy in the ribosomal protein, uS12/Rps23 (AJHG 2017 and Yale News March 9 2017 at https://news.yale.edu/2017/03/09/yale-team-helps-father-discover-source-…).
CREDIT: KL McCann, T Teramoto, J Zhang, TM Tanaka Hall, SJ Baserga. 2016. The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome. eLife.
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